- 📧 jgbastida@cebas.csic.es
- 📞 +34 968-396200 (ext. 6249)
- 🏢 Campus Universitario de Espinardo,Espinardo, Murcia, E-30100 (Spain)
Scientific career
During my Ph.D. period, I acquired multidisciplinary knowledge and experience in metabolic and molecular biology studies on cell and animal models of inflammation, resulting in 8 publications in high-impact factor journals, 4 posters and 1 oral presentation (international conferences). As a result, I received the cum laude distinction, the Extraordinary Doctorate Award and one Outstanding poster award in the 5th International Conference in Polyphenols and Health (Sitges, Spain).
The EU-funded Refresh project allowed me to work at the Institute of Animal Reproduction and Food Research (Olsztyn, Poland), where I studied the anti-inflammatory effects of buckwheat. I also mentored one pre-doctoral student and designed and managed my own experiments, publishing 2 papers as corresponding author, indicating ability to work without close supervision and independent thinking. I also attended the 252ND American Chemical Society National Meeting & Exposition (Philadelphia, EEUU) as invited speaker.
In 2014, I took a step in a new direction and joined Dr Schneider´s lab at Vanderbilt University (Nashville, TN, USA). Based on the objectives of the project I worked on, I produced quantitative data regarding the biochemical/chemical synthesis of eicosanoids and the study of their biological activity from a pharmacological approach. I also grew into many fruitful collaborations with many of the world leaders of eicosanoid research (Drs. John Oates, Stokes Peebles, and Ambra Pozzi). Thanks to the hard worked performed, I was awarded with one of the prestigious Postdoctoral Grants of the American Heart Association. This grant resulted in 7 publications in high-impact factor journals and numerous oral/poster presentations in international conferences, where I received 2 Travel and 1 Outstanding Poster awards. Besides, I also supervised 2 rotation students, established permanent international collaborations and acquired a background in nutrition and food science as well as in (clinical) pharmacology.
This multidisciplinary knowledge led me to be awarded with a Juan de la Cierva Fellowship to work at CEBAS-CSIC. The results obtained described novel roles of urolithins as pro-senescence molecules against cancer cells and new anti-inflammatory effects (targeting 5-LOX pathway) in leukocytes. The excellent results at the completion of this fellowship are reflected by 7 publications in high-impact factor journals and the obtained funding within the European Marie Curie program.
The EU-funded PolyBiota project (Grant Agreement ID: 838991) was a before and an after in my research career. It was an excellent bridge to continure the research line I started at CEBAS-CSIC, thus allowing me to branch out my research and knowledge base to the field of microbiology. The underlying thesis of PolyBiota was to consider the gut microbiota as mediator of the biological activity of (poly)phenols and their microbial metabolites. Hitherto, the project has provided interesting outcomes (i.e., celular and molecular mechanisms) about the essential role of the interaction between the gut microbiota and the dietary (poly)phenols to understand the beneficial effects related to their consumption. These results laid the foundation of different projects including (i) the CSIC-funded PolyBiota extension (18 months; 104,000€), (ii) the MCIU-funded Oxdyssey (36 months, 100,000€) and (iii) AngioPhenol (24 months; 146,000€) projects.
The AngioPhenol project puts angiogenesis in the spotlight of the tandem gut microbiota/(poly)phenols interaction to determine how their interaction targets this intrincate process related to the formation of new blood vessels from preexinting ones.
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